Overview

TemCam-XF416 is a high-resolution CMOS TEM camera optimized for low-dose cryo-EM, high-contrast imaging, and in-situ experiments. It combines fast 4k × 4k readout, ultra-high dynamic range, and low-noise performance for demanding scientific workflows.

Key Capabilities

• Up to 48 fps at full 4k × 4k resolution (higher frame rates for sub-areas)
• Ultra-high dynamic range using dual readout mode
• Real-time drift correction during acquisition
• Fiber-optical coupling for improved sensitivity
• TEC-cooled CMOS sensor in vacuum housing
• Optimized scintillators for 6–400 kV operation

System Requirements

• Windows 10 operating system
• Intel Quad-Core CPU
• Optical 40 Gigabit Ethernet interface
• PCI Express ×16 slot

Software

• EM-MENU
• Tomography
• Single Particle Collection
• EM-SPECTRO
• In-situ recording package (disk-based)

Applications

• Low-dose cryo-EM
• In-situ TEM experiments
• Materials science and life science imaging
• High-contrast and high-dynamic-range studies

Specifications

Sensor type	CMOS
Sensor resolution	4096 × 4096
Pixel size	15.5 µm × 15.5 µm
Field of view	63.5 × 63.5 mm²
Digitization	16 bit
Frame rate (full)	24 fps @ 4k × 4k
High-speed modes	Up to 190 fps (sub-area)
Electron-optical coupling	1:1 fiber optics
Sensor cooling	Thermoelectric (TEC)
Mounting position	On-axis or retractable

Specifications shown are typical values and may depend on configuration.